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  • Progressive supranuclear palsy

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    Progressive supranuclear palsy (PSP), also known as Steele–Richardson–Olszewski syndrome is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain. The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and dementia. PSP may be mistaken for other neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. The cause of the condition is uncertain but involves accumulation of tau protein within the brain. Medications such as levodopa and amantadine may be useful in some cases. PSP affects approximately six people per 100,000. The first symptoms typically occur in persons aged 60-70 years. Males are slightly more likely to be affected than females. There is no association between PSP and any particular race, location, or occupation.

  • Pseudobulbar palsy

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    Pseudobulbar palsy is a medical condition characterized by the inability to control facial movements (such as chewing and speaking) and caused by a variety of neurological disorders. Patients experience difficulty chewing and swallowing, have increased reflexes and spasticity in tongue and the bulbar region, and demonstrate slurred speech (which is often the initial presentation of the disorder), sometimes also demonstrating uncontrolled emotional outbursts. The condition is usually caused by the bilateral damage to corticobulbar pathways, which are upper motor neuron pathways that course from the cerebral cortex to nuclei of cranial nerves in the brain stem.

  • Neuritis

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    Neuritis () is inflammation of a nerve or the general inflammation of the peripheral nervous system. Symptoms depend on the nerves involved but may include pain, paresthesia (pins-and-needles), paresis (weakness), hypoesthesia (numbness), anesthesia, paralysis, wasting, and disappearance of the reflexes.

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