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  • Cholecalciferol

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    Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D which is made by the skin when exposed to sunlight, it also found in some foods and can be taken as a dietary supplement. It is used to treat and prevent vitamin D deficiency and associated diseases, including rickets. It is also used for familial hypophosphatemia, hypoparathyroidism that is causing low blood calcium, and Fanconi syndrome. It is usually taken by mouth. Excessive doses can result in vomiting, constipation, weakness, and confusion. Other risks include kidney stones. Normal doses are safe in pregnancy. It may not be effective in people with severe kidney disease. Cholecalciferol is made in the skin following UVB light exposure. It is converted in the liver to calcifediol (25-hydroxyvitamin D) which is then converted in the kidney to calcitriol (1,25-dihydroxyvitamin D). One of its actions is to increase the uptake of calcium by the intestines. It is found in food such as some fish, cheese, and eggs. Certain foods such as milk have cholecalciferol added to them in some countries. Cholecalciferol was first described in 1936. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Cholecalciferol is available as a generic medication and over the counter.

  • Hypervitaminosis D

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    Hypervitaminosis D is a state of vitamin D toxicity. The normal range for blood concentration is 30.0 to 74.0 nanograms per milliliter (ng/mL).

  • Caltrate

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    Caltrate is a brand name calcium supplement sold by Pfizer Consumer Healthcare and in Japan by Hisamitsu Pharmaceutical. The Caltrate brand is supplied in many different formulas; calcium carbonate (NOT calcium citrate) is the common ingredient serving as the calcium supplement source. Caltrate contains 600 mg of calcium carbonate as opposed to 200 mg in a typical multivitamin product. Citrate Plus also contains 800 IU of vitamin D (cholecalciferol), 20 mcg vitamin K1, 50 mg magnesium, 7.5 mg zinc oxide, 1 mg copper, and 1.8 mg of manganese (II) sulfate monohydrate.

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