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In this Article. White matter disease is the wearing away of tissue in the largest and deepest part of your brain due to aging. This tissue contains millions of nerve fibers, or axons, that connect other parts of the brain and spinal cord and signal your nerves to talk to one another. A fatty material called myelin protects...
White matter brain diseases have a variety of different symptoms that can impair visual, motor, sensory and cognitive functions. White Matter White matter is located in the central and subcortical regions of the cerebral and cerebellar hemisphere of the brain.
Overview. White matter disease is a disease that affects the nerves that link various parts of the brain to each other and to the spinal cord. These nerves are also called white matter. White matter disease causes these areas to decline in their functionality. This disease is also referred to as leukoaraiosis.
CT scan showed excessive brain matter. Increased white matter signal intensity would occur in infarcts and other conditions, while certain white matter degenerative diseases like adrenoleukodystrophies too may present with a similar picture. An MRI would be a much more useful investigation in most such cases to cofirm the diagnois, regards Dr. Gupta.
High blood pressure, atherosclerosis, inflammation and other basic disease processes may travel the brain on a superhighway of white matter, causing some of neurology's most mysterious and troubling disorders.
Yet white matter makes up half the human brain and has not been thought to be important in cognition or learning outside the context of pathology. That view could change. Imaging and cellular and molecular studies are revealing white matter plasticity with possible implications for normal cognitive function and psychological disorders.
3 Responses. Most often, white matter lesions are due to what is called "chronic small vessel disease", literally meaning diseased small vessels that supply blood flow to the brain. This is not an uncommon process in the brain and increases with age. This is not a disease in and of itself but rather is a reflection of unhealthy blood vessels,...
MRI of a child experiencing seizures. There are small foci of grey matter heterotopia in the corpus callosum, deep to the dysplastic cortex (double arrows)Gray matter heterotopia (singular heterotopion) is a neurological disorder caused by clumps of grey matter (ectopic nodules of neurons) located in the wrong part of the brain. It is characterized as a type of cortical dysplasia. The neurons in heterotopia appear to be normal, except for their mislocation; nuclear studies have shown glucose metabolism equal to that of normally positioned gray matter. The condition causes a variety of symptoms, but usually includes some degree of epilepsy or recurring seizures, and often affects the brain's ability to function on higher levels. Symptoms range from nonexistent to profound; the condition is occasionally discovered by brain imaging performed for an unrelated problem and has no apparent ill effect on the patient. At the other extreme, heterotopia can result in severe seizure disorder, loss of motor skills, and mental retardation. Fatalities are practically unknown, other than the death of unborn male fetuses with a specific genetic defect.
White matter structure of human brain (taken by MRI).White matter refers to areas of the central nervous system (CNS) that are mainly made up of myelinated axons, also called tracts. Long thought to be passive tissue, white matter affects learning and brain functions, modulating the distribution of action potentials, acting as a relay and coordinating communication between different brain regions. White matter is named for its relatively light appearance resulting from the lipid content of myelin. However, the tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color in prepared specimens is due to its usual preservation in formaldehyde.