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  • Dirofilaria immitis

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    Dirofilaria immitis, the heartworm or dog heartworm, is a parasitic roundworm that is a type of filarial worm, a small thread-like worm, that causes dirofilariasis. It is spread from host to host through the bites of mosquitoes. The definitive host is the dog, but it can also infect cats, wolves, coyotes, jackals, foxes, and other animals, such as ferrets, bears, seals, sea lions and, under rare circumstances, humans.Dirofilaria immitis is commonly called the "heartworm"; however, adults often reside in the pulmonary arterial system (lung arteries), as well as the heart, and a major effect on the health for the animal is a manifestation of damage to the lung vessels and tissues. Occasionally, adult heartworms migrate to the right heart and even the great veins in heavy infestations. Heartworm infection may result in serious disease for the host, with death typically as the result of congestive heart failure.

  • Angiostrongylus vasorum

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    Angiostrongylus vasorum, also known as French heartworm, is a species of parasitic nematode in the family Metastrongylidae. It causes the disease canine angiostrongylosis in dogs. It is not zoonotic, that is, it cannot be transmitted to humans. Not much is known about the biology of this species.

  • Moxidectin

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    Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms (helminths), such as heartworm and intestinal worms, in dogs, cats, horses, cattle and sheep. Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite.

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