Web Results
Content Results
  • Naproxen

    serch.it?q=Naproxen

    Naproxen, sold under the brand names Aleve and Naprosyn among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, menstrual cramps, inflammatory diseases such as rheumatoid arthritis, and fever. It is taken by mouth. It is available in an immediate and delay release formulation. Onset of effects is within an hour and last for up to twelve hours. Common side effects include dizziness, headache, bruising, allergic reactions, heartburn, and stomach pain. Severe side effects include an increased risk of heart disease, stroke, gastrointestinal bleeding, and stomach ulcers. The heart disease risk may be lower than with other NSAIDs. It is not recommended in people with kidney problems. Use is not recommended in the third trimester of pregnancy. Naproxen is a nonselective COX inhibitor. It is in the propionic acid class of medications. As an NSAID, naproxen appears to exert its anti-inflammatory action by reducing the production of inflammatory mediators called prostaglandins. It is metabolized by the liver to inactive metabolites. Naproxen was approved for medical use in the United States in 1976. It is available as a generic medication and over the counter. In the United Kingdom is costs about 0.15 pounds per dose. In the United States the wholesale cost per dose is less than US$0.10 as of 2018. In 2016 it was the 68th most prescribed medication in the United States with more than 11 million prescriptions.

  • Meloxicam

    serch.it?q=Meloxicam

    Meloxicam, sold under the brand name Mobic among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation in rheumatic diseases and osteoarthritis. It is taken by mouth. It is recommended that it be used for as short of period as possible and at a low dose. Common side effects include abdominal pain, dizziness, swelling, headache, and a rash. Serious side effects may include heart disease, stroke, kidney problems, and stomach ulcers. Use is not recommended in the third trimester of pregnancy. It blocks cyclooxygenase-2 (COX-2) more than it blocks cyclooxygenase-1 (COX-1). It is in the oxicam family of chemicals and is closely related to piroxicam. Meloxicam was approved for medical use in the United States in 2000. It was developed by Boehringer-Ingelheim, however is also available as a generic medication. In the United States the wholesale cost per dose is less than US$0.02 as of 2018. In the United Kingdom it costs about 0.13 pounds as of 2018. In 2016 it was the 36th most prescribed medication in the United States with more than 21 million prescriptions.

  • Aspirin exacerbated respiratory disease

    serch.it?q=Aspirin-exacerbated-respiratory-disease

    Aspirin exacerbated respiratory disease (AERD), also termed aspirin-induced asthma, is a medical condition initially defined as consisting of three key features: asthma, respiratory symptoms exacerbated by aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), and nasal polyps. The symptoms of respiratory reactions in this syndrome are hypersensitivity reactions to NSAIDs rather than the typically described true allergic reactions that trigger other common allergen-induced asthma, rhinitis, or hives. The NSAID-induced reactions do not appear to involve the common mediators of true allergic reactions, immunoglobulin E or T cells. Rather, AERD is a type of NSAID-induced hypersensitivity syndrome. EAACI/WHO classifies the syndrome as one of five types of NSAID hypersensitivity or NSAID hypersensitivity reactions.

Map Box 1