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Symptoms Duchenne type muscular dystrophy. This is the most common form of muscular dystrophy. Becker muscular dystrophy. Signs and symptoms are similar to those of Duchenne muscular dystrophy,... Other types of muscular dystrophy. Some types of muscular dystrophy are defined by a specific feature ...
Myotonic muscular dystrophy is the most common form of muscular dystrophy that affects adults and is characterized by myotonia, a symptom involving prolonged muscle stiffening or spasms that worsen in cold temperatures, explains WebMD. Other symptoms include daytime sleepiness, cataracts and heart problems, notes the Muscular Dystrophy Association.
In DM1, many of the involuntary muscles that surround the hollow organs can weaken. These include the muscles of the digestive tract, uterus, and blood vessels. The digestive tract and uterus (womb) often are affected in type 1 myotonic dystrophy. Also, symptoms such as colicky abdominal pain, bloating, constipation, and diarrhea are common.
Other symptoms of Becker muscular dystrophy include: walking on your toes. frequent falls. muscle cramps. trouble getting up from the floor.
Most of the symptoms of muscular dystrophy occur in children somewhere between the ages of 2 and 3. As the disease attacks the body, the muscles begin to weaken. Children may have difficulties putting pressure on their legs, or they may manifest other areas of weakness, especially around the ankles.
An adult-onset type of muscular dystrophy, facioscapulohumeral muscular dystrophy affects men and women equally. Symptoms first appear as weakness in the muscles of the face and shoulder girdle (upper arms and shoulders).
Gowers' signGowers' sign is a medical sign that indicates weakness of the proximal muscles, namely those of the lower limb. The sign describes a patient that has to use their hands and arms to "walk" up their own body from a squatting position due to lack of hip and thigh muscle strength. It is named after William Richard Gowers.
Congenital muscular dystrophies are autosomal recessively-inherited muscle diseases. They are a group of heterogeneous disorders characterized by muscle weakness which is present at birth and the different changes on muscle biopsy that ranges from myopathic to overtly dystrophic due to the age at which the biopsy takes place.
Muscular dystrophy (MD) is a group of muscle diseases that results in increasing weakening and breakdown of skeletal muscles over time. The disorders differ in which muscles are primarily affected, the degree of weakness, how fast they worsen, and when symptoms begin. Many people will eventually become unable to walk. Some types are also associated with problems in other organs. The muscular dystrophy group contains thirty different genetic disorders that are usually classified into nine main categories or types. The most common type is Duchenne muscular dystrophy (DMD) which typically affects males beginning around the age of four. Other types include Becker muscular dystrophy, facioscapulohumeral muscular dystrophy, and myotonic dystrophy. They are due to mutations in genes that are involved in making muscle proteins. This can occur due to either inheriting the defect from one's parents or the mutation occurring during early development. Disorders may be X-linked recessive, autosomal recessive, or autosomal dominant. Diagnosis often involves blood tests and genetic testing. There is no cure for muscular dystrophy. Physical therapy, braces, and corrective surgery may help with some symptoms. Assisted ventilation may be required in those with weakness of breathing muscles. Medications used include steroids to slow muscle degeneration, anticonvulsants to control seizures and some muscle activity, and immunosuppressants to delay damage to dying muscle cells. Outcomes depend on the specific type of disorder. Duchenne muscular dystrophy, which represents about half of all cases of muscular dystrophy, affects about one in 5,000 males at birth. Muscular dystrophy was first described in the 1830s by Charles Bell. The word "dystrophy" is from the Greek dys, meaning "difficult" and troph meaning "nourish". Gene therapy, as a treatment, is in the early stages of study in humans.