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Thalassemia is inherited, meaning that at least one of your parents must be a carrier of the disease. It’s caused by either a genetic mutation or a deletion of certain key gene fragments. Thalassemia minor is a less serious form of the disorder. There are two main forms of thalassemia that are more serious.
Thalassemia is really a group of blood problems, not just one. To make hemoglobin you need two proteins, alpha and beta. Without enough of one or the other, your red blood cells can’t carry oxygen as they should. Alpha thalassemia means you lack alpha hemoglobin. With beta thalassemia, you lack beta hemoglobin.
Mild thalassemia: people with thalassemia traits do not require medical or follow-up care after the initial diagnosis is made. People with β-thalassemia trait should be warned that their condition can be misdiagnosed as the more common iron deficiency anemia.
Thalassemia carrier is an individual who has one mutated gene that codes information for the normal production of red blood cells. A thalassemia patient has two or more defective genes. The thalassemia carrier is also known as thalassemia trait or thalassemia minor that has no direct impact on the health.
Thalassemia definition, a hereditary form of anemia, occurring chiefly in people of Mediterranean origin, marked by the abnormal synthesis of hemoglobin and a consequent shortened life span of red blood cells.
The thalassemias are a group of genetic (inherited) blood disorders that share in common one feature, the defective production of hemoglobin, the protein that enables red blood cells to carry and deliver oxygen. There are many different mechanisms of defective hemoglobin synthesis and, hence, many types of thalassemia.