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Alagille syndrome is a genetic disorder that can affect the liver, heart, and other parts of the body. One of the major features of Alagille syndrome is liver damage caused by abnormalities in the bile ducts. These ducts carry bile (which helps to digest fats) from the liver to the gallbladder and small intestine.
Alagille Syndrome is a genetic condition (associated with the Notch signaling pathway and Jagged1 gene) that causes narrowed and malformed bile ducts in the liver. Bile that cannot flow through the deformed ducts builds up in the liver and causes scarring.
Alagille syndrome is an autosomal dominant disorder, which means someone who carries the Jagged1 gene mutation has a 50 percent chance of passing on that mutation to their child. The effect of having a mutation in Jagged1 can vary widely.
Alagille syndrome is a genetic disorder in which you have fewer bile ducts than normal in your liver. Alagille syndrome can be passed from parent to child or happen naturally. Alagille syndrome not only affects the liver, it can also cause skin, heart, facial, kidney, and eye abnormalities.
Alagille syndrome is a rare inherited multisystem disorder that can affect the liver, heart, skeleton, eyes, kidneys and other parts of the body 1). One of the major features of Alagille syndrome is liver damage caused by abnormalities in the bile ducts.
Alagille syndrome is a genetic disorder that affects the liver, heart, and other systems of the body. Problems associated with the disorder generally become evident in infancy or early childhood.
Alagille syndrome is a genetic syndrome that can affect the liver and other parts of the body. The liver problems result from having fewer small bile ducts than normal in the liver. The liver problems result from having fewer small bile ducts than normal in the liver.
Alagille Syndrome is a major genetic disease found in infants. The preliminary affecting organ for Alagille Syndrome is the liver. The inherited disease has 50% chance of inheritance from the parents.
Alagille syndrome, Alagille-Watson syndrome or ALGS, is an autosomal dominant genetic disorder that affects the liver, heart, kidney, and other systems of the body. Problems associated with the disorder generally become evident in infancy or early childhood. The disorder is inherited in an autosomal dominant pattern, and the estimated prevalence of Alagille syndrome is 1 in every 100,000 live births. It is named for Daniel Alagille.
Daniel Alagille (24 January 1925 – 8 November 2005) was a French physician who specialized in pediatric hepatology, the study of childhood liver diseases.