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Diabetic kidney disease is a type of kidney disease caused by diabetes. Diabetes is the leading cause of kidney disease. The main job of the kidneys is to filter wastes and extra water out of your blood to make urine. Your kidneys also help control blood pressure and make hormones that your body needs to stay healthy.
Diabetic nephropathy -- kidney disease that results from diabetes-- is the number one cause of kidney failure. Almost a third of people with diabetes develop diabetic nephropathy.
Diabetic kidney disease (diabetic nephropathy) is a complication that occurs in some people with diabetes. In this condition the filters of the kidneys, the glomeruli, become damaged. Because of this the kidneys 'leak' abnormal amounts of protein from the blood into the urine.
Diabetic kidney disease (DKD) is the gradual and permanent loss of kidney function. This occurs because of kidney damage caused by high blood sugar levels. Normally, the kidneys remove fluid, chemicals, and waste from your blood. These wastes are turned into urine by your kidneys.
The predominant structural changes associated with diabetic kidney disease include mesangial expansion, glomerular basement membrane thickening and glomerular sclerosis28. The progression of DKD depends on many factors, and histologic patterns may be important 29 .
Diabetic kidney disease makes it harder for your kidneys to take waste out of your body. The problems gradually get worse as the disease moves through five stages. Treatment can help you manage ...